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In this study carried out at the Department of Oral and Maxillofacial Sciences-Prosthodontics Unit, University “Sapienza” of Rome has been evaluated the possibility to determine an individual correct vertical dimension of occlusion (VDO) through the use of surface electromyography (sEMG). A total of 20 patients that required a prosthetic implant oral rehabilitation were prospectively included in this study. For each patient three acquisitions EMG masseter and temporalis with a standardized protocol were performed. The determination of the VDO was obtained by modifying the provisional prosthesis with the aim of stabilizing the standardized indexes processed by the EMG apparatus software. The authors underlined that at the time of delivery of the final restoration, all sEMG standardized indexes showed values ??considered in the normal range. That instrumentally detect a perfectly integrated in the neuromuscular system occlusion and the individual correct VDO achievement. VDO occlusal adjustments are performed by evaluating the electrical muscle activity measured by EMG. The authors conclude that this procedure can positively affect the rehabilitation success rate because in neuromuscular balanced conditions overload components are reduced.